USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O95747 USC-OGP 2-DE database:  O95747 O95747 General information about the entry View entry in simple text format Entry name OXSR1_HUMAN Primary accession number O95747 Secondary accession number(s) Q7Z501 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Serine/threonine-protein kinase OSR1; EC=2.7.11.1; AltName: Full=Oxidative stress-responsive 1 protein;. Gene name Name=OXSR1 {ECO:0000312|HGNC:HGNC:8508} Synonyms=KIAA1101 {ECO:0000312|EMBL:BAA83053.2}, OSR1 {ECO:0000312|EMBL:BAA75674.1} Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1256: pI=5.39; Mw=30456 Cross-references UniProtKB/Swiss-Prot O95747; OXSR1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name OXSR1_HUMAN Primary accession number O95747 Secondary accession number(s) Q3LR53 Q7Z501 Q9UPQ1 Sequence was last modified on  May 1, 1999 (version 1) Annotations were last modified on  March 15, 2017 (version 162) Name and origin of the protein Description RecName: Full=Serine/threonine-protein kinase OSR1; EC=2.7.11.1; AltName: Full=Oxidative stress-responsive 1 protein; Gene name Name=OXSR1 {ECO:0000312|HGNC:HGNC:8508} Synonyms=KIAA1101 {ECO:0000312|EMBL:BAA83053.2}, OSR1 {ECO:0000312|EMBL:BAA75674.1} Encoded on Name=OXSR1 {ECO:0000312|HGNC:HGNC:8508}; Synonyms=KIAA1101 {ECO:0000312|EMBL:BAA83053.2}, OSR1 {ECO:0000312|EMBL:BAA75674.1 Keywords 3D-structure; Acetylation; ATP-binding; Complete proteome; Cytoplasm; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AB017642; BAA75674.1; -; mRNA EMBL AB029024; BAA83053.2; ALT_FRAME; mRNA EMBL DQ201638; ABA27097.1; -; Genomic_DNA EMBL BC008726; AAH08726.1; -; mRNA EMBL AF087893; AAP97192.1; ALT_INIT; mRNA CCDS CCDS2675.1; -; . RefSeq NP_005100.1; NM_005109.2; . UniGene Hs.475970; -; . PDB 2V3S; X-ray; 1.70 A; A/B=433-527 PDB 2VWI; X-ray; 2.15 A; A/B/C/D=1-303 PDB 3DAK; X-ray; 2.25 A; A/B/C/D=6-295 PDBsum 2V3S; -; . PDBsum 2VWI; -; . PDBsum 3DAK; -; . ProteinModelPortal O95747; -; . SMR O95747; -; . BioGrid 115269; 32; . DIP DIP-34977N; -; . IntAct O95747; 12; . MINT MINT-5207465; -; . STRING 9606.ENSP00000311713; -; . BindingDB O95747; -; . ChEMBL CHEMBL1163104; -; . GuidetoPHARMACOLOGY 2132; -; . iPTMnet O95747; -; . PhosphoSitePlus O95747; -; . SwissPalm O95747; -; . BioMuta OXSR1; -; . EPD O95747; -; . MaxQB O95747; -; . PaxDb O95747; -; . PeptideAtlas O95747; -; . PRIDE O95747; -; . DNASU 9943; -; . Ensembl ENST00000311806; ENSP00000311713; ENSG00000172939; . GeneID 9943; -; . KEGG hsa:9943; -; . UCSC uc003chy.4; human; . CTD 9943; -; . DisGeNET 9943; -; . GeneCards OXSR1; -; . HGNC HGNC:8508; OXSR1; . HPA CAB017181; -; . HPA HPA008237; -; . MIM 604046; gene; . neXtProt NX_O95747; -; . OpenTargets ENSG00000172939; -; . PharmGKB PA134973207; -; . eggNOG KOG0582; Eukaryota; . eggNOG ENOG410XSWS; LUCA; . GeneTree ENSGT00860000133680; -; . HOGENOM HOG000234204; -; . HOVERGEN HBG108518; -; . InParanoid O95747; -; . KO K08835; -; . OMA EPCIATI; -; . OrthoDB EOG091G0AKO; -; . PhylomeDB O95747; -; . TreeFam TF105339; -; . SignaLink O95747; -; . SIGNOR O95747; -; . ChiTaRS OXSR1; human; . EvolutionaryTrace O95747; -; . GeneWiki OXSR1; -; . GenomeRNAi 9943; -; . PRO PR:O95747; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000172939; -; . CleanEx HS_OSR1; -; . CleanEx HS_OXSR1; -; . ExpressionAtlas O95747; baseline and differential; . Genevisible O95747; HS; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005524; F:ATP binding; IDA:UniProtKB; . GO GO:0000287; F:magnesium ion binding; IDA:UniProtKB; . GO GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB; . GO GO:0004702; F:signal transducer; downstream of receptor; with serine/threonine kinase activity IBA:GO_Central . GO GO:0071476; P:cellular hypotonic response; IEA:Ensembl; . GO GO:0035556; P:intracellular signal transduction; IDA:UniProtKB; . GO GO:1901017; P:negative regulation of potassium ion transmembrane transporter activity; IEA:Ensembl; . GO GO:2000687; P:negative regulation of rubidium ion transmembrane transporter activity; IEA:Ensembl; . GO GO:0018107; P:peptidyl-threonine phosphorylation; IDA:ParkinsonsUK-UCL; . GO GO:0006468; P:protein phosphorylation; IDA:UniProtKB; . GO GO:0006979; P:response to oxidative stress; TAS:ProtInc; . InterPro IPR011009; Kinase-like_dom; . InterPro IPR024678; Kinase_OSR1/WNK_CCT; . InterPro IPR028749; Oxsr1; . InterPro IPR000719; Prot_kinase_dom; . InterPro IPR017441; Protein_kinase_ATP_BS; . PANTHER PTHR24361:SF435; PTHR24361:SF435; 1; . Pfam PF12202; OSR1_C; 1; . Pfam PF00069; Pkinase; 1; . SMART SM00220; S_TKc; 1; . SUPFAM SSF56112; SSF56112; 1; . PROSITE PS00107; PROTEIN_KINASE_ATP; 1; . PROSITE PS50011; PROTEIN_KINASE_DOM; 1; .

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